Supplementary Report on Experimental Autumn Crocus (Colchicum autumnale L.) Poisoning in Cattle: Morphological Evidence of Apoptosis

Journal of Veterinary Medical Science

Masaru KOBAYASHI¹  Takane MATSUI³  Manabu YAMADA³  Michio NAKAGAWA³  Makoto HARITANI²  Yoshiyasu KOBAYASHI³  Hidefumi FURUOKA³ 

[1] National Institute of Animal Health, 3-1-1 Kannondai, Tsukuba, Ibaraki 305-0856, Japan;Tohoku Branch Laboratory, National Institute of Animal Health, Shichinohe, Kamikita-gun, Aomori 039-2586, Japan;Department of Veterinary Pathology, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan

关键词: apoptosis;    autumn crocus (Colchicum autumnale L.);    cattle;   

DOI  :  10.1292/jvms.61.823

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(17)Cited-By(2)Previously we reported that tissue destruction characterized by the presence of karyopyknotic, karyorrhectic and mitotically arrested cells was seen in alimentary epithelial cells and lymphocytes in the lymphoid and hemopoietic systems of cattle experimentally administered with autumn crocus (Colchicum autumnale L.). This report deals with the mechanism of acute cellular injury following experimental autumn crocus poisoning in cattle as demonstrated by the in situ DNA strand break analysis and electron microscopy. The analyses revealed that cellular injury caused by autumn crocus was closely associated with apoptosis.

【 授权许可】

Unknown