Evaluation of quality of anesthesia and analgesia and of vital signs afterintramuscular administration of a combination of butorphanol, medetomidine and alfaxalonein cats

Journal of Veterinary Medical Science

Ran CHOI¹  Ye-Won KIM¹  Sang-Il SUH¹  Changbaig HYUN¹ 

[1] Section of Small Animal Internal Medicine, College of Veterinary Medicine, Kangwon National University, Chuncheon, Republic of Korea

关键词: alfaxalone;    anesthesia;    butorphanol;    domestic cat;    medetomidine;   

DOI  :  10.1292/jvms.15-0288

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(9)This study evaluated the quality of anesthesia, duration of analgesia and changes invital signs after intramuscular administration of a combination of butorphanol,medetomidine and alfaxalone in domestic cats. Ten healthy adult domestic cats (weighing2.9 ± 0.5 kg) were used in this study. Rectal temperature (T), pulse rate (PR),respiratory rate (fR) and systolic arterial pressure (SAP)were measured and recorded prior to intramuscular (IM) administration of butorphanol (0.2mg/kg), medetomidine (20 ug/kg) and alfaxalone (5 mg/kg) and then every10 min until return of consciousness. Qualitative scores for induction of anesthesia andrecovery were allocated, duration of anesthesia and recovery were calculated, and adverseevents were recorded. A needle prick with a 22-gauge hypodermic needle was used to assessanalgesia. Scores for induction and recovery quality were acceptable. No significantadverse events except nausea (7/10) and vomiting (5/10) were observed. The mean ± SD timesfrom induction to extubation and to standing (full recovery) were 114 ± 8 and 125 ± 7 min,respectively. There were statistically significant changes in PR,fR and SAP after induction of anesthesia. The combination ofbutorphanol, medetomidine and alfaxalone provided acceptable quality of anesthesia andanalgesia and exerted minimal cardiopulmonary effects in domestic cats.

【 授权许可】

Unknown