Japanese Journal of Infectious Diseases | |
Acute Encephalopathy Associated with Human Metapneumovirus Infection | |
Toshiaki Shimizu2  Keiji Kinoshita3  Takahiro Niizuma1  Akihisa Okumura2  | |
[1] Department of Pediatrics, Tokyo Rinkai Hospital;Department of Pediatrics, Juntendo University Faculty of Medicine;Department of Pediatrics, Koshigaya Municipal Hospital | |
关键词: human metapneumovirus; encephalopathy; interleukin-6; matrix metalloproteinase-9; | |
DOI : 10.7883/yoken.67.213 | |
学科分类:传染病学 | |
来源: National Institute of Infectious Diseases | |
【 摘 要 】
References(9)Cited-By(4)We encountered a 3.5-year-old girl with acute encephalopathy associated with human metapneumovirus (hMPV) infection. She had pyrexia and status epilepticus, followed by a coma. Cerebrospinal fluid analysis showed no pleocytosis or elevation of protein levels. hMPV RNA was detected in tracheal aspirate. Acute encephalopathy in the patient was probably related to the hMPV infection. Serum levels of interleukin-6 and matrix metalloproteinase-9 were elevated on admission, and these factors were presumed to be related to acute encephalopathy, associated with her viral infection, or due to status epilepticus. She was treated with dexamethasone pulse therapy, intravenous immunoglobulin, and continuous thiopental infusion. She recovered without neurological sequelae.
【 授权许可】
Unknown
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RO201911300838460ZK.pdf | 67KB | download |