Buschke-Lowenstein tumor: imiquimod therapy to esphincter preservation. Case report

Revista Brasileira de Coloproctologia

Azaro Filho, Euler de Medeiros¹  Codes, Lina Maria Góes de¹  Souza, Elias Luciano Quinto de¹  Bacellar, Melina da Silva¹  Mano, Aline Landim¹  Coelho, Fernanda Meira Pinto¹ 

[1]Hospital São Rafael

关键词: Condyloma acuminatum;    Imiquimod;    Buschke-;    Lowenstein tumor;    HPV;    Treatment;   

DOI  :  10.1590/S0101-98802008000300013

学科分类：心脏病和心血管学

来源: Sociedade Brasileira de Coloproctologia

【 摘 要 】

Buschke-Lowestein tumor or giant condyloma acuminatum is a verrucous, large lesion in the anorectal and perianal regions. It is not a malignant lesion in histopathologic findings. However, there is a risk of malignancy and trends an aggressive behavior. There is not a gold standard therapy, with the use of topical or systemic chemotherapy, immunotherapy, radiation therapy and large surgical resections. These surgical resections can be doing alone or in combinations with others therapies (multimodality therapy). The authors describe a case that the treatment option was the imiquimod cream 5%. The lesion invades in the anal sphincters, so fecal incontinence will result after surgery and a colostomy was mandatory. After 20 weeks treatment, the tumor presented a great regression, and it was treated with local excision and avoided a mutilating procedure.

【 授权许可】

CC BY-NC