Revista Cubana de Plantas Medicinales | |
Toxicological study of an aqueous extract from Enterolobium cyclocarpum (Jacq.) Griseb. duramen | |
Raya González, David3  Chávez Duran, Judith2  Morales López, María E.2  Castro Ortiz, Ricardo3  Urrutia Hernández, Sara E.3  Martínez Pacheco, Mauro Manuel3  Cajero Juárez, Marco1  | |
[1] Facultad de Medicina Veterinaria-CMEB, Morelia, México;Facultad de Ciencias Médicas y Biológicas Morelia, Morelia, México;Instituto de Investigaciones Químico Biológicas, Morelia, México | |
关键词: : IC50/LC50; crustacean; termite; rat; bacteria; fungus; oomicet; MCF-7 cells; | |
DOI : | |
学科分类:药理学 | |
来源: Editorial Ciencias Medicas | |
【 摘 要 】
Rationale: A protective effect of the aqueous extract from Enterolobium cyclocarpum (Jacq.) Griseb duramen on pinewood was reported. It was also attributed anti-nutritional and repellent action against dry wood termites Incisitermes marginipennis (Latreillé); it is considered a potential candidate for perishable dry wood preservation, whose possible toxicity must be studied.Objectives: To determine the toxicity of aqueous extract from E. cyclocarpum duramen.Methods: Mean inhibitory and lethal concentrations (IC50/LC50) of an aqueous extract from E. cyclocarpum duramen in organisms from different trophic levels.Results: LC50 for Artemia salina crustacean, I. marginipennis termite and Wistar rat were 1,3; 2 mg/mL and over 2 000 mg/kgind respectively. In microbial isolates, IC50 was 300 mg. In MCF-7 tumor cell line, IC50 was 1,3 mg.Conclusions: When comparing observed IC50/LC50 with allowable toxicity limits, it was concluded that the extract under study was not toxic for these organisms.
【 授权许可】
CC BY-NC
【 预 览 】
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RO201911300821651ZK.pdf | 80KB | download |