Discoid Lupus Erythematosus (DLE) in a Spitz Dog

Journal of Veterinary Medical Science

Ae-Ri JI²  Mi-Ran KI²  Tae-Hwan KIM²  Bruce H. WILLIAMS¹  Dong-Wei YUAN²  Il-Hwa HONG²  Jin-Kyu PARK²  Jung-Youn HAN²  Kyu-Shik JEONG²  Hai-Jie YANG²  Moon-Jung GOO² 

[1] Department of Veterinary Pathology, Armed Forces Institute of Pathology;Department of Pathology, College of Veterinary Medicine, Kyungpook National University

关键词: cutaneous lupus erythematosus;    interface dermatitis;    interface mural folliculitis;   

DOI  :  10.1292/jvms.70.633

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(12)Cited-By(2)A 3-year-old, female Spitz, was presented due to lack of response to therapies with a 6-month history of skin lesions characterized by diffuse erythema and scaling on the dorsal trunk. Physical examination revealed the dog was active and healthy. Skin culture isolated no fungus. Histological examination of skin biopsy specimens revealed interface dermatitis with hydropic degeneration of the basal layers, predominant plasmacytic perivascular accumulation in the dermis, and intensive plasma cell-rich interface mural folliculitis. Moderate CD3-positive lymphocytes infiltrated the superficial dermis. This report may provide unique information of canine discoid lupus erythematosus in an unusual breed with atypical cutaneous lesions.

【 授权许可】

Unknown