Phylogenetic relationship of Pasteurella pneumotropica Isolates from Laboratory Rodents Based on 16S rDNA Sequence

Journal of Veterinary Medical Science

Eiichi KAWAMOTO¹  Hiromi AMAO⁴  Hidehiro UESHIBA³  Hiraku SASAKI¹  Takuo SAWADA² 

[1] Animal Research Center, Tokyo Medical University;Department of Veterinary Microbiology, Nippon Veterinary and Animal Science University;Institute of Laboratory Animals, Tokyo Women's Medical University;Department of Laboratory Animal Science, Nippon Veterinary and Animal Science University

关键词: Pasteurella pneumotropica;    Phylogenetic analysis;    16S ribosomal DNA;   

DOI  :  10.1292/jvms.68.639

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(18)Cited-By(8)A 1344 bp fragment of the 16S ribosomal DNA (rDNA) sequence was used to determine the genetic relationship of Pasteurella pneumotropica isolates from laboratory rodents. A total of 30 nucleotide sequences of P. pneumotropica, including 24 wild strains, 3 reference strains, and 3 nucleotide sequences deposited in GenBank, were examined for heterogeneity of their 16S rDNA sequences. Phylogenetic analysis based on 16S rDNA sequence discriminated 5 types of branching lineages. Of these 5 types, 3 types had significant associations with mice or rats, and 2 had significant associations with the β-hemolytic phenotype. These results suggest that 16S rDNA sequencing of P. pneumotropica isolates demonstrates genetic heterogeneity and phylogenetic discrimination in terms of their hemolytic phenotype and host associations.

【 授权许可】

Unknown