Journal of Veterinary Medical Science | |
More effective induction of anesthesia using midazolam-butorphanol-ketamine-sevoflurane compared with ketamine-sevoflurane in the common marmoset monkey (Callithrix jacchus) | |
Hidetoshi ISHIBASHI1  | |
[1] Division of Primate Resources, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo 187�?8502, Japan | |
关键词: anesthesia induction; balanced anesthesia; multi-modal analgesia; non-human primate; pulse rate; | |
DOI : 10.1292/jvms.15-0099 | |
学科分类:兽医学 | |
来源: Japanese Society of Veterinary Science | |
【 摘 要 】
References(20)The common marmoset has been increasingly used for research in the biomedical field; however, there is little information available regarding effective methods of anesthesia in this species. This study retrospectively analyzed 2 regimens of anesthesia induction: intramuscular injection of ketamine followed by inhalation of 5% sevoflurane, and intramuscular injection of midazolam, butorphanol and ketamine followed by inhalation of 5% sevoflurane. Anesthetic depth did not reach the surgical anesthesia stage in 7 out of 99 animals receiving the former regimen, whereas there were only 2 such animals out of 273 receiving the latter regimen. The latter regimen, when followed by maintenance anesthesia with 3% sevoflurane inhalation, was successfully used in various nociceptive procedures. These results indicate that the injection of a combination of midazolam, butorphanol and ketamine followed by inhalation of a high concentration of sevoflurane is effective for anesthesia induction in marmosets.
【 授权许可】
Unknown
【 预 览 】
Files | Size | Format | View |
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RO201911300796797ZK.pdf | 463KB | download |