More effective induction of anesthesia using midazolam-butorphanol-ketamine-sevoflurane compared with ketamine-sevoflurane in the common marmoset monkey (Callithrix jacchus)

Journal of Veterinary Medical Science

Hidetoshi ISHIBASHI¹ 

[1] Division of Primate Resources, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo 187�?8502, Japan

关键词: anesthesia induction;    balanced anesthesia;    multi-modal analgesia;    non-human primate;    pulse rate;   

DOI  :  10.1292/jvms.15-0099

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(20)The common marmoset has been increasingly used for research in the biomedical field; however, there is little information available regarding effective methods of anesthesia in this species. This study retrospectively analyzed 2 regimens of anesthesia induction: intramuscular injection of ketamine followed by inhalation of 5% sevoflurane, and intramuscular injection of midazolam, butorphanol and ketamine followed by inhalation of 5% sevoflurane. Anesthetic depth did not reach the surgical anesthesia stage in 7 out of 99 animals receiving the former regimen, whereas there were only 2 such animals out of 273 receiving the latter regimen. The latter regimen, when followed by maintenance anesthesia with 3% sevoflurane inhalation, was successfully used in various nociceptive procedures. These results indicate that the injection of a combination of midazolam, butorphanol and ketamine followed by inhalation of a high concentration of sevoflurane is effective for anesthesia induction in marmosets.

【 授权许可】

Unknown