Measurement of Erythrocyte Volumes in Splenectomized Horses and Sham-Operated Horses at Rest and during Maximal Exercise

Journal of Veterinary Medical Science

Katsuyoshi KUBO²  Makoto KAI¹  Miyuki NARIZUKA³  Nobuhiko ITO³  Yoshinori FURUKAWA³  Sigeaki KATAOKA³  Atsushi HIRAGA¹  Iwao KUNUGIYAMA³ 

[1] Equine Research Institute, Japan Racing Association;Japan Livestock Technology Association;Department of Veterinary Radiology, School of Veterinary Medicine and Animal Sciences, Kitasato University

关键词: chromium-50;    equine;    erythrocyte volume;    plasma volume;    spleen;   

DOI  :  10.1292/jvms.59.733

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(16)Cited-By(3)Erythrocyte volumes of thoroughbred horses were measured. The volumes of splenectomized horses and sham-operated horses 2 hr after injection of 50Cr- tagged erythrocytes (at rest) and during maximal exercise were measured using the non-radioactive isotope 50Cr. Because splenic erythrocytes are released into circulation during exercise, it was estimated that the erythrocyte volumes of the sham-operated horses during maximal exercise are larger than those of the horses at rest. However, the erythrocyte volumes of the sham-operated horses at rest were about equal to those during maximal exercise. In the splenectomized horses, furthermore, erythrocyte volumes at rest and those at exercise were nearly equal. From these results, blood stored in the equine spleen is gradually mixed with circulating blood, and it was clarified that the phenomenon was completed within 2 hr. Although it is basically impossible to measure the circulating erythrocyte volume at rest using the erythrocyte tagged method, we observed that it is possible to measure the total erythrocyte volume using the 50Cr method. Also, the plasma volumes of the splenectomized horses during maximal exercise were found to be slightly smaller than those at rest. On the other hand, in the sham-operated horses, the plasma was decreased by a large quantity after maximal exercise. Therefore, it was suggested that the spleen participates in the phenomenon involving the disappearance of plasma from circulation due to exercise.

【 授权许可】

Unknown