Lipid peroxidation induced by Clinostomum detruncatum in muscle of the freshwater fish Rhamdia quelen

Diseases of Aquatic Organisms

S. F. Llesuy¹  E. Fortes¹  A. Belló-Klein¹  A. A. Belló¹  R. B. Robaldo¹  A. Bianchini¹  A. R. R. Belló¹ 

关键词: Parasite;    Oxidative stress;    Lipid peroxidation;    Fish;   

DOI  :  10.3354/dao042233

学科分类：生物科学（综合）

来源: Inter-Research

【 摘 要 】

ABSTRACT: The effect of Clinostomum detruncatum metacercaria infection on the activities of the antioxidant enzymes superoxide dismutase and catalase in muscle of the freshwater fish Rhamdia quelen was analyzed. Tert-butylhydroperoxide-initiated chemiluminescence, a measure of lipid peroxidation, was also investigated. Enzyme activities were similar in infected and uninfected fishes. However, the chemiluminescence was almost 2-fold higher in muscle of infected fishes thanin muscle of uninfected ones. These results indicate that parasite infection induces oxidative stress and a higher level of membrane damage in the fish muscle due to an imbalance between pro-oxidants and non-enzymatic antioxidants. Our results suggestthat fish response to parasite infection could involve, as in other vertebrates, reactive oxygen intermediates.

【 授权许可】

Unknown