Comparison of Salivary IgA Secretion Rate Collected by the Aspiration Method and SwabMethod

Bioscience of Microbiota, Food and Health

Noriyuki KOHDA¹  Yoshifumi KOTANI¹  Keiji KAKUMOTO²  Koji HAMURO¹  Masamichi TOBA¹ 

[1] Otsu Nutraceuticals Research Institute, Otsuka Pharmaceutical Co., Ltd., Japan;Information Management Office, Drug Safety Research Center, Tokushima Research Institute, Otsuka Pharmaceutical Co., Ltd., Japan

关键词: saliva collection;    IgA;    aspiration;    swab;   

DOI  :  10.12938/bmfh.32.107

学科分类：生物科学（综合）

来源: Nihon Bifizusukin Senta / Japan Bifidus Foundation

【 摘 要 】

References(33)Salivary immunoglobulin A (IgA) is used as an immunity marker, as saliva can be easily collected,noninvasively with little stress. However, several saliva collection methods can be used. Our comparisonbetween samples collected using different methods demonstrated that the salivary IgA secretion rate in samplescollected using an aspiration method was significantly correlated with that in samples collected using a swabmethod. Moreover, the significant circadian variation in salivary IgA secretion rate in the aspirated salivasuggested that the aspiration method does not suppress salivary IgA secretion rate variability compared withthe swab method. Therefore, the aspiration method should be considered as the preferable saliva collectionmethod.

【 授权许可】

Unknown