Journal of Veterinary Medical Science | |
Characterization of Equid Herpesvirus 1 (EHV-1) Related Viruses from Captive Grevy's Zebra and Blackbuck | |
Kerstin BORCHERS2  Hanns LUDWIG2  Frederik WIDÈN3  Dietmar LIECKFELDT2  Daniel BÖTTNER2  Arne LUDWIG2  George ALLEN4  Kai FRÖLICH1  Berndt KLINGEBORN2  | |
[1] Leibniz-Institute for Zoo and Wildlife Research Berlin;Institut für Virologie, FU Berlin, Königin-Luise-Str;Department of Virology, The National Veterinary Institute, (SVA);Department of Veterinary Science, Gluck Equine Research Center, Universitiy of Kentucky | |
关键词: antelope; equid alphaherpesvirus; zebra; | |
DOI : 10.1292/jvms.68.757 | |
学科分类:兽医学 | |
来源: Japanese Society of Veterinary Science | |
【 摘 要 】
References(22)Cited-By(6)Equid herpes virus 1 (EHV-1) related isolates from a captive blackbuck (strain Ro-1) and Grevy's zebra (strain T965) behaved similarly to EHV-1 and EHV-9 in respect to their host cell range. Restriction enzyme analysis and a phylogenetic tree confirmed that Ro-1 and T965 were identical and more closely related to EHV-1 than to EHV-9. Differences from EHV-1 became obvious firstly, by amino acid alignments revealing two unique substitutions in the gB protein of Ro-1 and T965. Secondly, an EHV-1 type-specific monoclonal antibody did not detect its antigen on Ro-1, T965 or EHV-9 infected cells by immunohistochemistry. The results support the view that Ro-1 and T965 isolates represent a distinct, previously unrecognized species of equid herpesviruses.
【 授权许可】
Unknown
【 预 览 】
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RO201911300764338ZK.pdf | 244KB | download |