Epidemiological Characteristics of Rubella and Congenital Rubella Syndrome in the 2012–2013 Epidemics in Tokyo, Japan

Japanese Journal of Infectious Diseases

Narumi Hori⁵  Shigetaka Katow¹  Naotaka Shimatani³  Takuri Takahashi²  Yoshiyuki Sugishita⁴ 

[1] Center of Research Network for Infectious Diseases, RIKEN;Infectious Disease Surveillance Center, National Institute of Infectious Diseases;Okayama University Medical School;Epidemiological Information Section, Tokyo Metropolitan Institute of Public Health;Disease Control and Prevention Center, National Center for Global Health and Medicine

关键词: adult rubella;    CRS;    outbreak;    vaccination;    pregnant woman;   

DOI  :  10.7883/yoken.JJID.2014.195

学科分类：传染病学

来源: National Institute of Infectious Diseases

【 摘 要 】

References(16)Cited-By(4)A large rubella outbreak has been observed since June 2012 in Tokyo, Japan, and a rapid increase in the number of congenital rubella syndrome (CRS) cases have also been reported in Japan since October 2012. All the clinically diagnosed and laboratory-confirmed rubella cases reported in Tokyo from January 2012 to December 2013 and all the laboratory-confirmed CRS cases from January 2012 to March 2014 were analyzed. In total, 4,116 rubella cases were reported in Tokyo. Of these, 77.2% (n = 3,176) were male; the highest number of cases occurred in males aged 35–39 years and in females aged 20–24 years. Complications included arthralgia/arthritis (19.4%), thrombocytopenic purpura (0.5%), hepatic dysfunction (0.3%), and encephalitis (0.1%). The circulating rubella virus in Tokyo was genotype 2B. The most possible site of transmission was the workplace. Because of the rubella epidemic, 16 CRS cases were reported in Tokyo from March 2013 to February 2014. Domestic infection with rubella was proven for all mothers of 16 cases. This situation suggests that Japan is still working to achieve rubella elimination.

【 授权许可】

Unknown