Congenital hypogammaglobulinemia associated with granulocyte disorders.: A case presentation

Revista Cubana de Hematología, Inmunología y Hemoterapia

Núñez Quintana, Aramís¹  Sánchez Segura, Miriam C.²  Macías Abraham, Consuelo¹  Ojeda de León, Norma¹  Arce Hernández, Ada A.¹  Insua Arregui, Concepción¹  Marsán Suárez, Vianed¹  del Valle Pérez, Lázaro O.¹  Socarrás Ferrer, Bertha B.¹ 

[1] Instituto de Hematología e Inmunología, Ciudad de La Habana, Cuba

关键词: Hypogammaglobulinemia;    primary immunodeficiency;    neutropenia;    phagocytosis;   

DOI  :  

学科分类：生理学与病理学

来源: SciELO

【 摘 要 】

This is the case of a child aged 11 months with a history of systemic sepsis from Pseudomona aeruginosa at 5 months, neutropenia, leucopenia, sepsis-associated anemia and from then, recurrent acute respiratory infections of the high respiratory tract, allergic manifestations and furunculosis from pseudomona. Immunologic study conducted showed a decreased figure of IgG with a light increase of CD4+ cooperative-IgM of T cells. Also, we found the presence of neutropenia and marked defect of phagocytosis. We made the diagnosis of granulocyte-associate congenital hypogammaglobulinemia. The patient was treated with human gamma globulin by intramuscular route, transference factor and immunoferon, with an obvious improvement.  

【 授权许可】

CC BY-NC