Characterization of cycloartanol triterpene isolated from dichloromethane extract of Pedilanthus tithymaloides

Revista Cubana de Plantas Medicinales

Cuellar Cuellar, Armando²  Cabrera Suárez, Hirán³  Pita, Roberto Carlo¹ 

[1] Synthetic Antigen Center, La Habana, Cuba;Pharmacy and Food Institute, La Habana, Cuba;Central Laboratory of Pharmacology (LCF), La Habana, Cuba

关键词: : Pedilanthus tithymaloides;    Cycloartanol;    Triterpene;    Itamo real;    Phytochemistry;   

DOI  :  

学科分类：药理学

来源: Editorial Ciencias Medicas

【 摘 要 】

Introduction: Pedilanthus tithymaloides is known as ítamo real and it has been previously reported as an alternative to treatment of oral cavity virus infections. Objective: to explain procedures to characterize one of the major compounds isolated from dichloromethane extracts of Pedilanthus tithymaloides (L.) Poit (leaves). Methods: it was obtained cycloartanol from dichloromethane extract modifying polarity of the solvents with methanol and by increasing polarity to extract, they were used chromatography technique and spectroscopic of nuclear magnetic resonance H+ and 13C to characterize this compounds. Results: phytochemical studies showed quality parameters that were similar to average limits in the use of majority of medicinal plants except total ashes assay (13 %), qualitative determination assay suggest presence of reducers compounds, quinone, phenols and/or tannins, triterpene and/or steroids. And they were compared spectrum carbon 13 (13C) of the substance obtained from extract of this plant with other reported in literature to cycloartanol and found coincidence in majority of carbons compared. Conclusions: cycloartanol triterpene was one of main compounds of dichloromethane extract of Pedilanthus tithymaloides (L) Poit leaves.

【 授权许可】

CC BY-NC