Relationships among fecal daidzein metabolites, dietary habit and BMI in healthy volunteers: a preliminary study

Bioscience of Microbiota, Food and Health

Yuji NAITO¹  Kazuhiro KATADA¹  Motoi TAMURA²  Toshikazu YOSHIKAWA¹  Kazuhiro KAMADA¹  Hiroyuki NAKAGAWA²  Sachiko HORI²  Kazuhiko UCHIYAMA¹  Tomohisa TAKAGI¹  Osamu HANDA¹ 

[1] Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachidori Hirokojiagaru, Kamigyo-ku, Kyoto 602-8566, Japan;National Food Research Institute of the National Agriculture and Food Research Organization, 2-1-12, Kannondai, Tsukuba, Ibaraki 305-8642, Japan

关键词: daidzein;    dihydrodaidzein;    equol;    microbiota;   

DOI  :  10.12938/bmfh.2014-019

学科分类：生物科学（综合）

来源: Nihon Bifizusukin Senta / Japan Bifidus Foundation

【 摘 要 】

References(27)Cited-By(2)To investigate the relationships among fecal isoflavone metabolism, dietary habit and Body Mass Index (BMI), 15 healthy men and 15 healthy women were recruited and provided stool samples for analysis of ex vivo anaerobic incubation of fecal suspension with daidzein. A negative correlation was observed between BMI and the dihydrodaidzein (DHD) production in men, and between BMI and the equol production in women. There was a positive correlation between intake of soluble dietary fiber and the DHD production in men. The results suggest that dietary habits and BMI are related to the metabolic activity of isoflavonoids by fecal intestinal microbiota.

【 授权许可】

Unknown