Stability on shelf (second year) of a gel from the Rhizophora mangle L.

Revista de Salud Animal

Escobar, A¹  Soler, Dulce María¹  Llanes, Marisleidys¹  Pérez, Zulema¹  Morales, I²  Riverón, Yamilka¹  Rodríguez, Yanet¹  Pérez, Tania¹ 

[1] Centro Nacional de Sanidad Agropecuaria (CENSA), Mayabeque, Cuba;Centro de Investigación y Desarrollo de Medicamentos (CIDEM), La Habana, Cuba

关键词: stability;    gel;    Rhizophora mangle L;   

DOI  :  

学科分类：兽医学

来源: Centro Nacional de Sanidad Agropecuaria

【 摘 要 】

A long-term shelf stability or shelf life of a formulation is a critical factor in obtaining a quality product; moreover in natural products since they are often prone to deterioration, especially during storage. The stability of three pilot batches of a semisolid gel was evaluated at 5 ± 3 ºC during the second year. They were obtained from R. mangle L bark aqueous extract. Lots were produced at pilot scale and packaged in internally lacquered aluminum tubes of 25 g. Physical-chemical and microbiological indicators were evaluated after 24 months of storage and compared with those obtained at the initial time and after 12 months. All batches showed stable organoleptic properties, pH 6 to 7, extensibility area of 30-50 cm2, microbial limit <102 CFU/g, antimicrobial activity between 8-10 mg/g and rheological behavior of a non-newtonian fluid type Herschel Bulkley, without significant differences with the earlier times. The concentration of total tannins showed variation over time; however, this indicator was within the acceptance limit for a 13-30 mg/g formulation. These results allowed proposing a shelf life of the product of two years under the storage conditions tested.

【 授权许可】

Unknown