Acromegaly with Polycystic Ovaries, Hyperandroenism, Hirsutism, Insulin Resistance and Acantliosis Nigricans

Endocrine Journal

ALI ÜNAL¹  YILMAZ SAHIN²  FAHRETTIN KELESTIMUR¹ 

[1] Department of Internal Medicine, Erciyes University School of Medicine;Department of Obstetrics and Gynecology, Erciyes University School of Medicine

关键词: Acromegaly;    Polycystic ovary;    Acanthosis nigricans;    Insulin resistance;    Hyperandrogenism;   

DOI  :  10.1507/endocrj.40.207

学科分类：内分泌与代谢学

来源: Japan Endocrine Society

【 摘 要 】

References(18)Cited-By(9)We describe a woman with acromegaly who had acanthosis nigricans and hirsutism. Serum growth hormone (GH) and testosterone levels were markedly elevated. Standard oral glucose tolerance test (OGTT) showed a diabetic curve and no suppressed GH levels. Fasting insulin levels were very high while plasma glucose levels were not hypoglycemic. Insulin tolerance test revealed blunted hypoglycemic response. Acanthosis nigricans was present in the right axilla and face. Ultrasonogram demonstrated bilateral polycystic changes in the ovaries. From the above findings this patient's condition is characteristic of a very rare syndrome consisting of acromegaly, polycystic ovaries (PCO), hyperandrogenism, hirsutism, insulin resistance and acanthosis nigricans.

【 授权许可】

Unknown