期刊论文详细信息
Journal of Veterinary Medical Science
Effects of Androgen on Plasma Levels of Adrenocorticotropic Hormone and Cortisol during Transportation in Goats
Yuko MAEJIMA2  Atsushi TOHEI1  Satoko KEYAKI2  Misako MUROI2  Shoei SUGITA2  Masato AOYAMA2 
[1] Laboratory Animal Research Center, Dokkyo University School of Medicine;Faculty of Agriculture, Utsunomiya University
关键词: ACTH;    androgen;    cortisol;    goat;    transportation stress;   
DOI  :  10.1292/jvms.67.1109
学科分类:兽医学
来源: Japanese Society of Veterinary Science
PDF
【 摘 要 】

References(20)Cited-By(6)Previously, we demonstrated that plasma cortisol (Cor) levels were increased by road transportation in castrated male goats, but the extent of the increase was significantly reduced by 5α-dihydrotestosterone (DHT) implantation. This study aims to clarify whether the reduction of Cor secretion by androgen during transportation results from reduced plasma adrenocorticotropic hormone (ACTH). Castrated goats were implanted separately with cholesterol (Cho), testosterone (T) or DHT, followed by transportation. Plasma Cor levels increased during transportation regardless of hormone treatment, but the levels in T and DHT treated animals were lower than those in animals treated with Cho. Plasma ACTH levels also increased during transportation, and those in T treated animals were significantly lower than in those treated with Cho. However, plasma ACTH levels in DHT treated animals varied among the animals and did not differ from those in Cho treated animals. Significant and highly positive correlations between the logarithm of plasma ACTH levels and plasma Cor levels were found in every treatment group. The areas under the regression curves between plasma ACTH levels and plasma Cor levels associated with T and DHT treatments were significantly lower than those with Cho treatment. In conclusion, T was shown to reduce ACTH secretion in response to transportation in castrated goats. However, this suppression of the increase in Cor secretion during transportation by androgen is suggested to be mainly a result of suppression of the responsiveness of the adrenal cortex to ACTH.

【 授权许可】

Unknown   

【 预 览 】
附件列表
Files Size Format View
RO201911300706563ZK.pdf 172KB PDF download
  文献评价指标  
  下载次数:5次 浏览次数:6次