Symptomatic Tongue Atrophy Due to Atypical Polymyositis in a Pembroke Welsh Corgi

Journal of Veterinary Medical Science

Toshihiro WATARI⁴  Masato KITAGAWA⁴  Midori OKADA²  Daisuke ITO⁴  Kazuyuki UCHIDA³  Nick D. JEFFERY¹ 

[1] Department of Veterinary Medicine, University of Cambridge;Nihon University, School of Veterinary Research Center;Department of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, The University of Tokyo;Nihon University, School of Veterinary Medicine

关键词: canine;    dog;    myopathy;    myositis;   

DOI  :  10.1292/jvms.71.1063

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(16)A three-year-old, 7.3-kg, female Pembroke Welsh Corgi exhibited symptomatic tongue atrophy, crinkling of the tip of the tongue, dysphagia and excessive salivation. Neurological examination suggested multiple cranial neuropathy, but polymyositis was diagnosed by magnetic resonance imaging and muscle biopsy. The dog did not respond to prednisolone treatment and died from aspiration pneumonia 22 months after the first presentation. Post-mortem histopathological examination of the tongue revealed marked myofiber loss and fibrosis with multifocal infiltration of mixed mononuclear cells. Similar findings were also observed in the masticatory muscles and quadriceps without abnormality of peripheral nerves or evidence of infection. Symptomatic tongue atrophy occurring in the course of polymyositis has not been reported previously in dogs.

【 授权许可】

Unknown