Detection and Phylogenetic Analysis of Hepatitis E Viruses from Mongooses in Okinawa, Japan

Journal of Veterinary Medical Science

Minoru NIDAIRA¹  Masaji NAKAMURA³  Go OGURA²  Jun KUDAKA¹  Kazuaki TAKAHASHI⁴  Kiyomasa ITOKAZU¹  Shou OKANO¹  Katsuya TAIRA¹  Shunji MISHIRO⁴ 

[1] Department of Biological Sciences, Okinawa Prefectural Institute of Health and Environment, 2085 Ozato, Nanjo, Okinawa 901–1202, Japan;Laboratory of Subtropical Zoology, Faculty of Agriculture, University of The Ryukyus, 1 Senbaru, Nishihara, Okinawa 903–0213, Japan;Okinawa Prefectural Chuo Meat Inspection Center, 2015 Ozato, Nanjo, Okinawa 901–1202, Japan;Department of Medical Sciences, Toshiba General Hospital, 6–3–22 Higashi Oh-i, Shinagawa-ku, Tokyo 140–8522, Japan

关键词: hepatitis E virus;    mongoose;    Okinawa;    phylogenetic analysis;   

DOI  :  10.1292/jvms.11-0520

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(20)Cited-By(14)Hepatitis E virus (HEV) infection has previously been reported in wild mongooses on Okinawa Island; to date however, only one HEV RNA sequence has been identified in a mongoose. Hence, this study was performed to detect HEV RNA in 209 wild mongooses on Okinawa Island. Six (2.9%) samples tested positive for HEV RNA. Phylogenetic analysis revealed that 6 HEV RNAs belonged to genotype 3 and were classified into groups A and B. In group B, mongoose-derived HEV sequences were very similar to mongoose HEV previously detected on Okinawa Island, as well as to those of a pig. This investigation emphasized the possibility that the mongoose is a reservoir animal for HEV on Okinawa Island.

【 授权许可】

Unknown