Seroepidemiology of Reovirus in Healthy Dogs in Six Prefectures inJapan

Journal of Veterinary Medical Science

Masami MOCHIZUKI¹  Masaru OKUDA³  Takuya MIZUNO³  Ken MAEDA²  Chung Chew HWANG³ 

[1] Emerging Infectious Diseases, Joint Faculty of Veterinary Medicine, Kagoshima University, 1�?21�?24 Korimoto, Kagoshima 890�?0065, Japan;Laboratory of Veterinary Microbiology, Joint Faculty of Veterinary Medicine, Yamaguchi University, 1677�?1 Yoshida, Yamaguchi 753�?8515, Japan;Laboratory of Veterinary Internal Medicine, The United Graduate School of Veterinary Science, Yamaguchi University, 1677�?1 Yoshida, Yamaguchi 753�?8515, Japan

关键词: canine;    neutralizing antibody;    plaque reduction neutralization test;    reovirus;    seroepidemiology;   

DOI  :  10.1292/jvms.13-0472

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(33)Cited-By(1)Reovirus infection is common in mammals. However, seroepidemiological data ofreovirus neutralizing antibodies are limited in dogs. In this study, sera of 65 healthydogs from six prefectures across Japan were tested for neutralizing antibodies againstreovirus serotype 1 strain Lang (T1L), serotype 2 strain Amy (T2A) and serotype 3 strainDearing (T3D) using plaque reduction neutralization test (PRNT). Seropositivity againstreovirus T1L, T2A and T3D was 53.85%, 33.85% and 46.15%, respectively. Distribution ofreovirus seropositive samples displayed no distinguishable geographical pattern. However,reovirus seropositivity increased with age and in dogs housed outdoor. Co-infection ofmultiple reovirus serotypes in dogs was also detected. These data will provide valuableinsights towards the usage of reovirus in oncolytic virotherapy in canine cancers.

【 授权许可】

Unknown