Strategies to prevent HIV transmission to serodiscordant couples

Revista Brasileira de Epidemiologia

Raxach, Juan Carlos¹  Hallal, Ronaldo Campos²  Barcellos, Nêmora Tregnago⁴  Maksud, Ivia³ 

[1] Associação Brasileira Interdisciplinar de AIDS, Rio de Janeiro, Brasil;Santa Casa de Porto Alegre, Porto Alegre, Brasil;Fundação Oswaldo Cruz, Rio de Janeiro, Brasil;Universidade do Vale do Rio dos Sinos, Porto Alegre, Brazil

关键词:  Acquired immunodeficiency syndrome;    Health care;    Sexuality;    HIV seroposivity;    Health services;    Health public policyINTRODUCTIONNew studies about reducing the risks of sexual transmission of HIV by employing strategies combined with the use of antiretrovirals (ARV) extend possibilities of intervention for serodiscordant couples (partners with different serology for HIV);   

DOI  :  10.1590/1809-4503201500050013

学科分类：过敏症与临床免疫学

来源: SciELO

【 摘 要 】

Introduction: The use antiretroviral reduces the sexual transmission of HIV, expanding interventions for serodiscordant couples. Objective:This article aims to review the use of antiretroviral and other prevention interventions among serodiscordant couples and to analyze its use in Brazil.Methods:A retrospective review was performed through the MEDLINE database and bases included in the Biblioteca Virtual em Saúde.Results:The articles recovered exhibit four main strategies: (1) condom; (2) reduction of risks in sexual practices; (3) use of antiretrovirals, particularly early initiation of antiretroviral therapy (TASP) and pre-exposure prophylaxis (PrEP); (4) risk reduction in reproduction. Discussion: TASP is highly effective in reducing sexual transmission, PrEP was tested in serodiscordant couples and both reduce the sexual transmission risk in different sexual practices, enabling individualized prevention strategies.Conclusions:When used in combination, antiretrovirals and sexual practices with condoms offer greater efficacy than any single strategy. The combined use of new and old strategies allows us to build a prevention policy for all.

【 授权许可】

Unknown