Experimental infection models and susceptibility of Atlantic salmon Salmo salar to a Scottish isolate of infectious salmon anaemia virus

Diseases of Aquatic Organisms

R. S. Raynard¹  D. W. Bruno¹  M. Snow¹ 

关键词: Infectious salmon anaemia virus;    Atlantic salmon;    Salmo salar;    Experimental infection;   

DOI  :  10.3354/dao047169

学科分类：生物科学（综合）

来源: Inter-Research

【 摘 要 】

ABSTRACT: Infection models for both fresh and seawater salmon were established using a Scottish isolate of infectious salmon anaemia virus (ISAV). Modes of infection were intra-peritoneal injection, cohabitation and immersion exposure, and a range ofdoses was tested. Development of these models using a Scottish isolate of ISAV provided an approximation of the minimum infective dose leading to mortality under different infection regimens. The models also allow prediction of the time to first mortalityand an estimation of expected total mortality following the various routes of infection. Such knowledge is important to the development of anti-ISAV vaccines and to future studies aimed at understanding the biology of ISAV in general.

【 授权许可】

Unknown