Effects of CRH and LHRH on Rat Septo-Hippocampal Neurons

Endocrine Journal

TAKASHI OSADA¹ 

[1] Department of Physiology, Yokohama City University School of Medicine

关键词: Septum;    Diagonal band of Broca;    CRH;    LHRH;    Extracellular recording;   

DOI  :  10.1507/endocrj.44.519

学科分类：内分泌与代谢学

来源: Japan Endocrine Society

【 摘 要 】

References(37)Cited-By(4)Electrical activities of septum-diagonal band neurons (SD neurons) antidromically activated by electrical stimulation of the fimbria were recorded in urethane anesthetized male rats. The mean basal firing rate of antidromically identified SD neurons (2.3Hz) was not different from that of unidentified ones (2.2Hz). The mean latency of antidromic activation by the fimbria stimulation was 4.2 ms. Iontophoretically applied CRH and LHRH affected 60% and 40% of identified SD neurons, but only 19% and 13% of unidentified SD neurons, respectively. The ratio of response to no response to both peptides was significantly different in unidentified SD neurons from that in identified SD neurons. These results suggest that SD neurons mediate the effect of CRH and LHRH on hippocampal neurons.

【 授权许可】

Unknown