Molecular Epidemiological Analysis of Bat Rabies Viruses in Brazil

Journal of Veterinary Medical Science

Samir I. SAMARA⁴  Darci P. NOCITI⁴  Takeo SAKAI¹  Tetsuo SATO¹  Fumio H. ITO²  Elenice M. S. CUNHA³  Youko SHOJI¹  Adolorata A. B. CARVALHO⁴  Takuya ITOU¹  Yuki KOBAYASHI¹  Go SATO¹ 

[1] Department of Preventive Veterinary Medicine and Animal Health, School of Veterinary Medicine, Nihon University;Faculty of Veterinary Medicine and Zootechny, University of Sao Paulo;Research and Development Center for Animal Sanitation Biological Institute, Sao Paulo State Agency of Agribusiness;Faculty of Agriculture and Veterinary Science, University of Sao Paulo

关键词: bat;    Brazil;    molecular epidemiology;    rabies;   

DOI  :  10.1292/jvms.67.647

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(21)Cited-By(18)A molecular epidemiological analysis was performed in 19 rabies viruses (RVs) isolated from haematophagous, frugivorous and insectivorous bats, in Sao Paulo, Brazil. The authors carried out RT-PCR for amplification of the RV nucleoprotein (N) gene, and determined 1,335 nucleotide sequences of N gene by direct sequencing method. Phylogenetic analysis, which was based on the N gene of Brazilian RV isolates identified presently and previously, revealed that RVs isolated from bats were genetically divided into four lineages had a tendency to depend on the host bat species. The first lineage consisted mainly of haematophagous bat (Desmodus rotundus) isolates, including frugivorous bat (Artibeus spp.) isolates. Other three lineages consisted of insectivorous bat isolates; mainly Eptesicus spp., Molossus spp. and Nyctinomops spp. isolates, respectively. These results indicate a possibility of that there are bat species-specific RV variants in Brazil.

【 授权许可】

Unknown