4-Hydroxy-2-methyl-N-(2-thiazole)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide (EX15) and its Cu(II) Complex as New Oxicam Selective Cyclooxygenase-2 Inhibitors

Croatica Chemica Acta

El-Asmy, Ahmed Abdel-Hamid³  Sherif, Yousery El-Sayed¹  Lotfy, Mahmoud² 

[1] Department of Chemistry, Faculty of Science and Arts, Olla, Taibah University, Kingdom of Saudi Arabia;Molecular Biology Department, Genetic Engineering and Biotechnology Research Institute, Minufiya University, Sadat City, Minufiya, Egypt;Department of Chemistry, Faculty of Science, Mansoura University, Mansoura, Egypt

关键词: Oxicam;    metal complexes;    analgesic;    rheumatoid;    anti-inflammatory;   

DOI  :  

学科分类：化学（综合）

来源: Croatica Chemica Acta

【 摘 要 】

4-Hydroxy-2-methyl-N-(2-thiazole)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide (EX15) as nonsteroidal antiinflammatory drug (NSAIDs) of oxicam family has been synthesized bearing high se-lectivity for cyclooxygenase-2 (COX-2)...

【 授权许可】

Unknown