Allogeneic bone graft devitalized in liquid nitrogen - sheep experimental study

Ciência Rural

Alievi, Marcelo Meller¹  Albuquerque, Paulo Barros de²  Gianotti, Giordano Cabral²  Pinto, Thadeu Mourão²  Silva, Renato Barbosa²  Moura, Lanucha Fidelis da Luz²  Barni, Brunna de Souza¹  Boss, Mariana Zacouteguy¹ 

[1]UFRGS, Porto Alegre, Brazil

[2]Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil

关键词: allogeneic bone graft;    incorporation;    dynamic compressive plate;    orthopedics;    ovine;   

DOI  :  10.1590/0103-8478cr20140006

学科分类：农业科学（综合）

来源: Universidade Federal de Santa Maria * Centro de Ciencias Rurais

【 摘 要 】

This study evaluated the allogeneic cortical bone graft incorporation after submission of the harvested fragment to a bout freezing in liquid nitrogen. Six adult sheep, clinically healthy, were submitted to a 7cm ostectomy of the tibial diaphysis. The fragment was submersed in a liquid nitrogen and implanted in another sheep missing a same-sized segment at the corresponding bone. Stabilization of the allograft in the host bone was accomplished by a dynamic compressive plate (DCP). Clinical and radiographic evaluations were performed in the immediate post-operatory period and in every 30 days for six months after surgery. The proximal and distal host-graft interfaces showed radiographic union at a mean postoperative time of 95 days in all the animals. The cortical bone allograft submitted to liquid nitrogen freezing provided adequate bone healing in the sheep model

【 授权许可】

Unknown