Follicular Thyroid Carcinoma Characterized by Abundant Stromal Components with Chondroid and Osseous Metaplasia in a Dog

Journal of Veterinary Medical Science

Minoru TSUCHITANI³  Junko SATO³  Ryosuke KOBAYASHI³  Takuya DOI³  Yumi WAKO³  Kazunari SATO²  Takashi KITAMORI¹  Naoaki YAMADA³  Fumiyo KITAMORI¹ 

[1] Kitamori Animal Hospital, 2368 Kobayashi, Mobara-shi, Chiba 297�?0074, Japan;Minamikoyasu Animal Hospital, 5�?12�?8 Minamikoyasu, Kimitsu-shi, Chiba 299�?1162, Japan;Pathology Department, LSI Medience Corporation, 14�?1 Sunayama, Kamisu-shi, Ibaraki 314�?0255, Japan

关键词: canine;    chondroid metaplasia;    follicular thyroid carcinoma;    osseous metaplasia;    tumor stroma;   

DOI  :  10.1292/jvms.13-0529

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(8)Cited-By(2)A dog developed a cervical mass, and computed tomography verified a mass surrounding the trachea with some pulmonary masses. Histopathologically, the cervical mass was composed of malignant neoplastic cells showing follicular appearance which reacted positive for thyroglobulin on immunohistochemistry. A characteristic feature of the tumor was abundant and metaplastic stromal components. Anastomosed collagenous tissues connecting to capsule of the tumor were abundant in the stroma. In parts of the collagenous tissues, mature cartilages and bones were continuously formed. There was no cellular atypia or invasion in the components. We diagnosed this case as follicular thyroid carcinoma with metaplastic stroma. This is the first case report that characterizes stromal components with chondroid and osseous metaplasia in a canine thyroid carcinoma.

【 授权许可】

Unknown