Session 2: Personalised nutrition Transcriptomic signatures that have identified key features of metabolic syndrome: Symposium on ‘The challenge of translating nutrition research into public health nutrition’

Proceedings of the Nutrition Society

Melissa J. Morine¹  Cathal O'Brien¹  Helen M. Roche¹ 

关键词: Nutrigenomics;    Transcriptomic signatures;    Metabolic syndrome;   

DOI  :  10.1017/S0029665108008756

学科分类：卫生学

来源: Cambridge University Press

【 摘 要 】

The Human Genome Project and rapid advances in high-throughput molecular technologies are providing an unprecedented opportunity to advance the understanding of the common polygenic diet-related diseases, including obesity, the metabolic syndrome, type 2 diabetes mellitus, CVD and some cancers. In particular, transcriptomic approaches that allow multiple simultaneous gene-expression profiles facilitate the characterisation of metabolic perturbations that underlie diet-related pathologies. The present paper will focus on ‘transcriptomic signatures’ to characterise and understand the molecular mechanisms that accurately reflect ‘metabolic health’.

【 授权许可】

Unknown