Effect of Bordetella bronchiseptica and Serotype D Pasteurella multocida Bacterin-Toxoid on the Occurrence of Atrophic Rhinitis after Experimental Infection with B. bronchiseptica and Toxigenic Type A P. multocida

Journal of Veterinary Medical Science

Shizuo SATO¹  Munenori OKADA¹  Tetsuya SAKANO¹  Tetsuya MUKAI²  Atsuyoshi TANEDA¹ 

[1] Zen-noh Institute of Animal Health;Synthetic Feed Laboratory Co., Ltd.

关键词: atrophic rhinitis;    bacterin-toxoid;    Pasteurella multocida;   

DOI  :  10.1292/jvms.59.55

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(37)Cited-By(5)In efficacy tests, 7 primary specific-pathogen-free piglets vaccinated with the Bordetella bronchiseptica and type D Pasteurella multocida bacterin-toxoid were challenged with B. bronchiseptica and type A P. multocida. Severe or moderate nasal turbinate atrophy was produced in the non-vaccinated pigs, whereas, only one of the 4 pigs in the vaccinated group had slight turbinate atrophy. Other immune sera against crude toxin of P. multocida type A or D were cross neutralized. The results of the present study show that the P. multocida serotype D bacterin-toxoid is effective against atrophic rhinitis caused by toxigenic P. multocida serotype A as well as toxigenic P. multocida serotype D.

【 授权许可】

Unknown