Public Health Nutrition | |
Analysis of patterns of food intake in nutritional epidemiology: food classification in principal components analysis and the subsequent impact on estimates for endometrial cancer | |
James R Marshall1  Saxon Graham1  Jo L Freudenheim1  Susan E McCann1  John R Brasure1  | |
关键词: Dietary patterns; Endometrial cancer; Statistical methods; | |
DOI : 10.1079/PHN2001168 | |
学科分类:卫生学 | |
来源: Cambridge University Press | |
【 摘 要 】
Objective:To assess the effect of different methods of classifying food use on principal components analysis (PCA)-derived dietary patterns, and the subsequent impact on estimation of cancer risk associated with the different patterns.Methods:Dietary data were obtained from 232 endometrial cancer cases and 639 controls (Western New York Diet Study) using a 190-item semi-quantitative food-frequency questionnaire. Dietary patterns were generated using PCA and three methods of classifying food use: 168 single foods and beverages; 56 detailed food groups, foods and beverages; and 36 less-detailed groups and single food items.Results:Classification method affected neither the number nor character of the patterns identified. However, total variance explained in food use increased as the detail included in the PCA decreased (~8%, 168 items to ~17%, 36 items). Conversely, reduced detail in PCA tended to attenuate the odds ratio (OR) associated with the healthy patterns (OR 0.55, 95% confidence interval (CI) 0.35–0.84 and OR 0.77, 95% CI 0.49–1.20, 168 and 36 items, respectively) but not the high-fat patterns (OR 0.95, 95% CI 0.57–1.58 and OR 0.85, 0.51–1.40, 168 and 36 items, respectively).Conclusions:Greater detail in food-use information may be desirable in determination of dietary patterns for more precise estimates of disease risk.
【 授权许可】
Unknown
【 预 览 】
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RO201911300594519ZK.pdf | 126KB | download |