期刊论文详细信息
Diseases of Aquatic Organisms
Efficacy of a Listonella anguillarum (syn. Vibrio anguillarum) vaccine for juvenile sea bass Dicentrarchus labrax
Panagiotis Angelidis1  Dimitrios Karagiannis Elizabeth M. Crump1 
关键词: Immersion;    Vaccination;    Dicentrarchus labrax;    Vibrio anguillarum;    Listonella anguillarum;    Vibriosis;   
DOI  :  10.3354/dao071019
学科分类:生物科学(综合)
来源: Inter-Research
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【 摘 要 】

ABSTRACT: The efficacy of a commercial bivalent Listonella anguillarum (serotype 01 and 02) vaccine (MICROViB, Microtek International) was tested on prime- and booster-immersion vaccinated sea bass Dicentrarchus labrax juveniles. We carried out 2 challenge tests on the prime-vaccinated fish, 50 and 90 d after initial vaccination. A second group of fish received a booster vaccination 60 d after the prime vaccination, and were tested with a single challenge 30 d later. Relative percent survival (RPS) was 92 and 84% (both p < 0.01) among the prime-vaccinated fish on the first and second challenges, respectively. The RPS of the booster-vaccinated sea bass was 100% (p < 0.01). Antibody titres were tested only among 10 prime-vaccinated and 10 unvaccinated (control) sea bass, 60 d post-immunisation, and were found to rise to 1/32 in the vaccinated fish. Our results demonstrate that MICROViB immersion vaccine can effectively protect juvenile sea bass from L. anguillarum infection.

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