期刊论文详细信息
Journal of Veterinary Medical Science
Effect of Attenuated Erysipelothrix rhusiopathiae Vaccine in Pigs Infected with Porcine Reproductive Respiratory Syndrome Virus
Takayuki OSUMI1  Takanori NAMIMATSU1  Masahumi MORI1  Katsuyoshi URUNO1  Tetsuya SAKANO1  Isao SHIBATA1  Masaaki ONO1 
[1] Zen-noh Institute of Animal Health
关键词: Erysipelothrix rhusiopathiae;    experimental infection;    PRRS;    swine;    vaccine;   
DOI  :  10.1292/jvms.59.977
学科分类:兽医学
来源: Japanese Society of Veterinary Science
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【 摘 要 】

References(17)Cited-By(1)Twenty 2nd specific pathogen-free pigs were divided into 4 groups: Group A were infected with porcine reproductive and respiratory syndrome (PRRS) virus at 6 weeks of age and treated with available swine erysipelas and swine fever combined vaccine (vaccinated) at 7 weeks of age; Group B were vaccinated at 7 weeks of age and infected with PRRS virus at 8 weeks of age; Group C were vaccinated at 7 weeks of age: Group D were neither vaccinated nor infected with PRRS virus. All pigs were challenged to Erysipelothrix rhusiopathiae C42 strain at 10 weeks of age. No clinical signs appeared after vaccination of group A and B pigs, thus confirming that the safety of the vaccine was not influenced by infection with PRRS virus. None of the pigs in Groups A and C developed erysipelas after challenge exposure to E. rhusiopathiae. In contrast, fever and/or urticaria appeared transiently in all pigs of Group B after challenge exposure. At the time of challenge exposure to E. rhusiopathiae, the PRRS virus titer was high in sera of Group B, but was low in those from Group A. However, vaccination of pigs with attenuated E. rhusiopathiae was effective in dual infection with PRRS virus and E. rhusiopathiae, because the clinical signs were milder and the E. rhusiopathiae strain was less recovered from these pigs compared to pigs of group D.

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