Successful Management of Multidrug-Resistant Pseudomonasaeruginosa Pneumonia after Kidney Transplantation in aDog

Journal of Veterinary Medical Science

Heung-Myong WOO¹  Kyung-Mee PARK¹  Hyun-Suk NAM¹ 

[1] Section of Veterinary Surgery, College of Veterinary Medicine, Kangwon National University, Chuncheon 200�?701, Republic of Korea

关键词: canine;    immunosuppressants;    pneumonia;    Pseudomonas;    renal transplantation;   

DOI  :  10.1292/jvms.13-0194

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(23)Cited-By(3)An 8-year-old male mongrel dog that had undergone renal transplantation was presented 25days later with an acute cough, anorexia and exercise intolerance. During theinvestigation, neutrophilic leukocytosis was noted, and thoracic radiographs revealedcaudal lung lobe infiltration. While being treated with two broad-spectrum antibiotics,clinical signs worsened. Pneumonia due to infection with multidrug-resistant (MDR)Pseudomonas (P.) aeruginosa, sensitive only to imipenem and amikacin,was confirmed by bacteria isolation. After treatment with imipenem-cilastatin withoutreducing the immunosuppressant dose, clinical signs completely resolved. During the 2-yearfollow-up period, no recurrence was observed. To the best of authors�? knowledge, this isthe first report of pneumonia caused by MDR P. aeruginosa in a renalrecipient dog and successful management of this disease.

【 授权许可】

Unknown