Sugar Expressions on the Vaginal Epithelium in Pregnant Mice

Journal of Veterinary Medical Science

Tetsuya SHIMOKAWA¹  Motowo NABETA³  Aya MATSUU⁴  Atsushi ASANO⁵  Youhei YASUNAGA²  Takashi TAKEUCHI²  Yasuhiko OHTA² 

[1] Department of Anatomy and Embryology, Ehime University School of Medicine, Toh-on, Ehime 791-0295, Japan;Department of Laboratory Animal Science, Faculty of Agriculture, Tottori University, Tottori 680-8553, Japan;Department of Obstetrics and Gynecology, Ehime University School of Medicine, Toh-on, Ehime 791-0295, Japan;Department of Veterinary Internal Medicine, Faculty of Agriculture, Tottori University, Tottori 680-8553, Japan;Department of Veterinary Biochemistry, Faculty of Agriculture, Tottori University, Tottori 680-8553, Japan

关键词: lectin;    mouse;    pregnancy;    sugar;    vagina;   

DOI  :  10.1292/jvms.11-0562

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(18)Sugar expressions were examined on the epithelium of both the middle portion of the vagina and the vaginal portion of the cervical canal (CC) in pregnant mice to understand the pathogenesis of bacterial infection in the female reproductive organ by using a panel of lectins. As a result, N-acetylglucosamine was positive before pregnant day (P) 7 but negative after P10 and at diestrus on both the vagina and the CC. In addition, some differences in sugar expressions were seen between them. These results suggest that sugar expressions on the mucosal surface would change not only site-specifically but also time-dependently, and these sugar differences indicate the possibility of the alteration of the settled bacterial species on the vaginal mucosa in pregnancy.

【 授权许可】

Unknown