Evaluation of antimicrobial and modulatory activity of the ethanol extract of Libidibia ferrea (Mart. ex Tul.) L.P. Queiroz

Revista Cubana de Plantas Medicinales

Figueiredo Leite, Nadghia¹  Sabino Albuquerque, Rosimeire¹  Martins da Costa, José Galberto¹  Ferreira de Lima, Luciene¹  Gomes Figueredo, Fernando¹  Ferreira Matias, Edinardo Fagner¹  de Alencar Ferreira, João Victor¹  Bezerra da Cunha, Francisco Assis¹  Cosmo Andrade, Jacqueline¹  Bezerra Morais Braga, Maria Flaviana¹  Sobral de Souza, Elba¹  Tintino, Saulo Relison¹  Melo Coutinho, Henrique Douglas¹ 

[1] Universidade Regional do Cariri, Brasil

关键词: Libidibia ferrea;    antimicrobial activity;    resistance to change;   

DOI  :  

学科分类：药理学

来源: Editorial Ciencias Medicas

【 摘 要 】

Introduction:Staphylococcus aureus is mentioned in the literature as an important pathogen, some opportunistic bacteria may cause several problems in many animals and humans. Escherichia coli is a leading cause of human infectious diseases. Belonging to the family Enterobacteriaceae, share many virulence factors described by their resistance to multiple antibiotics, the contamination is probably initiated by modifications in the host defenses. Pseudomonas aeruginosa is known to cause acute infection by producing toxins.Objective:evaluate the antimicrobial effect of the ethanol extract of Libidibia ferrea (Mart ex Tul.) LP Queiroz, and modulation of antibiotic activity.Methods:L. ferrea was collected in the municipality of Penaforte, Ceará, Brazil. To obtain the extracts were collected bark and fruits, submerged in ethanol separately for 72 h, after this period, filtered and concentrated in a rotary vacuum condenser. Antimicrobial activity tests were performed and modulation of antimicrobial activity with standards and multiresistant strains of bacteria.Results:the extract showed antibacterial activity when combined with some antibiotics against the assayed strains, demonstrating a modulatory potential.Conclusion:therefore, it is suggested that L. ferrea extract can be used as a source of natural products in the antimicrobial therapy and in the combat bacterial multidrug resistance.

【 授权许可】

CC BY-NC