Public Health Nutrition | |
Iodine status during pregnancy in India and related neonatal and infant outcomes | |
Dattatray S Bhat1  Morven IFA Lean1  Chittaranjan S Yajnik1  Suyog M Joshi1  Mike EJ Lean1  Emilie Combet1  Deepa A Raut1  Himangi G Lubree1  | |
关键词: Iodine; Nutrition; Prevention; Pregnancy; India; Neonatal outcomes; Infant outcomes; | |
DOI : 10.1017/S1368980013001201 | |
学科分类:卫生学 | |
来源: Cambridge University Press | |
【 摘 要 】
AbstractObjectiveTo document iodine status in Indian pregnancies, associations with maternal diet and demographics, and offspring developmental measures.DesignLongitudinal study following mothers through pregnancy and offspring up to 24 months.SettingRural health-care centre (Vadu) and urban antenatal clinic (Pune) in the Maharashtra region of India.SubjectsPregnant mothers at 17 (n 132) and 34 weeks’ (n 151) gestation and their infants from birth to the age of 24 months.ResultsMedian urinary iodine concentration (UIC) was 203 and 211 μg/l at 17 and 34 weeks of pregnancy, respectively (range 26–800 μg/l). Using the UIC distribution adjusted for within-person variation, extreme UIC quartiles were compared for predictors and outcomes. There was no correlation between UIC at 17 and 34 weeks, but 24 % of those with UIC in the lowest quartile at 17 weeks had UIC in the same lowest quartile at 34 weeks. Maternal educational, socio-economic status and milk products consumption (frequency) were different between the lowest and highest quartile of UIC at 34 weeks. Selected offspring developmental outcomes differed between the lowest and highest UIC quartiles (abdominal circumference at 24 months, subscapular and triceps skinfolds at 12 and 24 months). However, UIC was only a weak predictor of subscapular skinfold at 12 months and of triceps skinfold at 24 months.ConclusionsMedian UIC in this pregnant population suggested adequate dietary provision at both gestational stages studied. Occasional high results found in spot samples may indicate intermittent consumption of iodine-rich foods. Maternal UIC had limited influence on offspring developmental outcomes.
【 授权许可】
Unknown
【 预 览 】
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