Histoplanimetrical Study on the Spatial Relationship of Distribution of Indigenous Bacteria with Mucosal Lymphatic Follicles in Alimentary Tract of Rat

Journal of Veterinary Medical Science

Yuh YOKOO¹  Hidenori MIYATA¹  Kenkichi YAMAMOTO²  Wang-Mei QI²  Junichi KAWANO¹  Nobuhiko HOSHI²  Kankanam Gamage Sanath UDAYANGA¹  Hiroshi KITAGAWA²  Toshifumi YOKOYAMA² 

[1] Department of Bioresource Science, Graduate School of Agricultural Science, Kobe University;Department of Bioresource and Agrobiosciences, Graduate School of Science and Technology, Kobe University

关键词: alimentary tract;    histology;    lymphoid organ;    microbiological monitoring;    rat;   

DOI  :  10.1292/jvms.71.621

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(30)Cited-By(10)The spatial relationship between the distribution of indigenous bacteria (IB) and the situation of mucosal lymphatic follicles (LF) is histoplanimetrically studied in the rat alimentary tract. From the oral cavity to the nonglandular part of the stomach, IB adhered to the corneal layer of the most luminal mucosa. In the glandular part of the stomach, IB adhered only to the most luminal mucosa but not in the gastric pits. In the small intestine, IB consistently adhered around the apices of both intestinal villi and the domes, and their amounts decreased toward their basal portions. No IB entered the intestinal crypts. In the large intestine, IB consistently adhered to the most luminal mucosa. Numerous IB were suspended in the intestinal crypts of both the cecum and the proximal colon, whereas there were no IB in the crypts of the distal colon and the rectum. When IB spread over the basal portions of the intestinal villi, IB with the same morphology were detected on the neighboring LF, whereas no bacteria were detected on the neighboring LF, when IB were located in the apical to middle portions of the intestinal villi. This close relationship between the distribution of IB and mucosal LF was also observed in the large intestine. These results suggest that the most luminal mucosae are a fundamental settlement site of IB throughout the alimentary tract and that the hyperproliferation of IB's colonies might be detected by neighboring LF in the rat intestine.

【 授权许可】

Unknown