Hypophysectomy for a Dog with Coexisting Cushing's Disease and Diabetes Mellitus

Journal of Veterinary Medical Science

Hidekazu KOYAMA¹  Yasuji HARADA⁵  Shigeki TANAKA³  Takahiro TESHIMA⁵  Akira TERAMOTO⁴  Susumu TAKEKOSHI²  Robert Y. OSAMURA²  Yasushi HARA⁵  Toshinori SAKO⁴  Hirokazu ISHINO⁵  Takuya YOGO⁵  Yoshinori NEZU⁵  Masahiro TAGAWA⁵ 

[1] Division of Veterinary Internal Medicine, Department of Veterinary Science, Faculty of Veterinary Medicine, Nippon Veterinary and Life Science University;Department of Pathology, Tokai University School of Medicine;Alpha Animal Hospital;Department of Veterinary Nursing, Faculty of Veterinary Medicine, Nippon Veterinary and Life Science University;Division of Veterinary Surgery, Department of Veterinary Science, Faculty of Veterinary Medicine, Nippon Veterinary and Life Science University

关键词: canine;    Cushing's disease;    diabetes mellitus;    hypophysectomy;    pituitary;   

DOI  :  10.1292/jvms.09-0348

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(33)An 11-year-old male mixed breed dog diagnosed with Cushing's disease and diabetes mellitus was treated by hypophysectomy. After surgery, the hypercortisolemia disappeared and the diabetes status improved. The insulin requirement to control hyperglycemia gradually decreased. At 12 weeks after surgery, there was no requirement for insulin and we suspected the diabetes was completely resolved. In the present case, diabetes mellitus seems to be secondary to Cushing's disease. In conclusion, this mixed breed dog with coexisting Cushing's disease and diabetes mellitus is the first case showing the effectiveness of hypophysectomy to treat diabetes mellitus secondary to Cushing's disease in dogs.

【 授权许可】

Unknown