Comparative Studies on the Distribution and Population of Immunocompetent Cells in Bovine Hemal Node, Lymph Node and Spleen

Journal of Veterinary Medical Science

Weidong ZHANG²  Tetsuo NASU²  Yoshinao Z. HOSAKA¹  Masahiro YASUDA² 

[1] Department of Veterinary Anatomy, Faculty of Agriculture, Tottori University, Tottori 680-8550, Japan;Department of Veterinary Anatomy, Faculty of Agriculture, University of Miyazaki, Miyazaki 889-2192, Japan

关键词: comparative study;    flow cytometry;    hemal node;    immunocompetent cells;    immunohistochemistry;   

DOI  :  10.1292/jvms.11-0405

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(42)Cited-By(3)The distribution and population of immunocompetent cells in bovine hemal node, mesenteric lymph node and spleen were analyzed comparatively by immunohistochemistry and flow cytometry. Many CD8+ cells, CD172a+ cells and γδT cells were found in the lymphatic cord along the sinus of the hemal node and the splenic red pulp. A few CD8+ cells and γδT cells were distributed diffusely in the paracortex and medullary cord of the mesenteric lymph node. Many germinal centers were recognized in the lymphatic regions such as the cortex and white pulp of these lymphoid organs. The populations of CD8+ cells and γδ T cells in the hemal node and the spleen were higher than those of the mesenteric lymph node. In addition, the populations of CD21+ cells and MHC class II+ cells in the hemal node and the mesenteric lymph node were higher than those of the spleen. The results suggest that the hemal node has an important role in both cellular and humoral immunity as well as the lymph node and the spleen in cattle.

【 授权许可】

Unknown