Tissue engineering for temporomandibular joint disc repair and regeneration: a methodological perspective

Advances in Cellular and Molecular Otolaryngology

Pedro Morouço²  David Ângelo¹  Luís Francisco¹  Carla Moura¹  Nuno Alves¹ 

[1] Polytechnic Institute of LeiriaCentre for Rapid and Sustainable Product Development

关键词: temporomandibular joint;    tissue engineering;    scaffolds;   

DOI  :  

来源: Co-Action Publishing

【 摘 要 】

This perspective aims to highlight some of the methodological issues in tissue engineering, using the temporomandibular joint (TMJ) disc as an example. Knowing that disorders affecting the TMJ are quiet common and that implants that mimic such a complex structure remain a paramount challenge, tissue engineering has engaged in some efforts to solve this issue. Furthermore, tissue engineering should be considered a multidisciplinary scientific field, applying a wide variety of methodologies, thus requiring multidisciplinary research teams, to provide suitable inputs for its development. From our perspective, it is possible to corroborate that significant improvements have been done for engineering the TMJ disc; however,in vivotrials are scarce suggesting that further research is mandatory to obtain results that may lead to translational medicine.Published: 30 November 2016Citation: Advances in Cellular and Molecular Otolaryngology 2016, 4: 33709 - http://dx.doi.org/10.3402/acmo.v4.33709

【 授权许可】

Unknown