Plasma Leptin Concentration in Dogs with Diabetes Mellitus

Journal of Veterinary Medical Science

Masaki TAKASU⁴  Naohito NISHII¹  Satoshi TAKASHIMA⁵  Miho YAMASAKI⁵  Hitoshi KITAGAWA⁵  Tsutomu HONJOH²  Yasunori OHBA⁵  Haruki SHIBATA²  Yoshihiko OTSUKA³ 

[1] Laboratory of Veterinary Pharmacotherapeutics, Faculty of Agriculture, Tottori University;Morinaga Institute of Biological Science, Inc.;Mitsubishi Chemical Medience Corporation;Laboratory of Veterinary Clinical Theriogenology, Faculty of Applied Biological Sciences, Gifu University;Laboratory of Veterinary Internal Medicine, Faculty of Applied Biological Sciences, Gifu University

关键词: canine;    diabetes;    insulin;    leptin;   

DOI  :  10.1292/jvms.09-0481

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(16)Cited-By(1)The plasma leptin concentration was evaluated in dogs with diabetes mellitus. Twenty normal and sixteen diabetic dogs were divided into nonobese and obese groups based on body condition score, respectively. The obese normal dogs had significantly higher plasma leptin concentrations than the nonobese normal dogs, whereas there was no significant difference between the nonobese and obese diabetic dogs. In addition, the plasma leptin concentration in the obese diabetic dogs was significantly lower than that in the obese normal dogs. In conclusion, the plasma leptin concentrations in the diabetic dogs were affected by factors other than adiposity.

【 授权许可】

Unknown