Primary Subcutaneous Leiomyosarcoma of the Hamster Hind Leg

Journal of Veterinary Medical Science

Yeong-Hun KIM¹  Jung-Yeon YI¹  Byung-Il YOON¹ 

[1] School of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University

关键词: hamster;    hind leg;    subcutaneous leiomyosarcoma;   

DOI  :  10.1292/jvms.70.517

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(21)Cited-By(3)We report the first case of a primary subcutaneous leiomyosarcoma that originated in the hind leg of a hamster and metastasized to the bone marrow, lung and diaphragm. A 10-month-old female Syrian golden hamster was presented with a large, firm, white subcutaneous mass in the right hind leg. The tumor invaded into the bone marrow and small nodules were also present in the lung and diaphragm; however, no tumor masses were found in the visceral organs. Histologically, the tumors were spindle cell sarcomas, composed of densely packed pleomorphic spindle cells with oval to elongate nuclei and moderate amounts of eosinophilic cytoplasm. Immunohistochemically, the neoplastic cells were positive for vimentin, desmin, and smooth muscle actin, but negative for α-sarcomeric actin and S-100. Thus, the diagnosis was primary leiomyosarcoma of the hind leg with metastasis to the bone marrow, lung and diaphragm. To the best of our knowledge, this is the first report of spontaneous primary subcutaneous leiomyosarcoma of the hind leg with distant metastasis in laboratory animals.

【 授权许可】

Unknown