Phylogenetic analysis of Newcastle disease viruses isolated from wild birdsin the Poyang Lake region of China

Journal of Veterinary Medical Science

Songtao YANG²  Ying YING⁵  Xianzhu XIA²  Yongcheng LI¹  Tiecheng WANG²  Dong CHU¹  Shengtao FAN⁴  Qihan LI⁴  Xiaolong GAO³  Yuanguo LI²  Jinzhu MA²  Heting SUN¹  Yu XU¹  Xue LI²  Yuwei GAO² 

[1] General Station for surveillance of wildlife Diseases & Wildlife Borne Disease, State Forestry Administration, Shenyang 110086, PR China;Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Institute of Military Veterinary, Academy of Military Medical Sciences, No. 666, Liuying Xilu, Jingyue Economic Development Zone, Changchun 130122, PR China;State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150001, PR China;Institute of Medical Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Kunming 650118, PR China;College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, PR China

关键词: genotype;    Newcastle disease virus;    phylogenetic analysis;    Poyang Lake;   

DOI  :  10.1292/jvms.14-0080

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(30)Cited-By(3)Supplementary materials(1)Newcastle disease virus (NDV) causes a highly contagious viral disease in poultry andwild birds, and it can cause significant economic loss worldwide. Eight viral strains wereisolated by inoculating embryonated chicken eggs from the Poyang Lake region of China withswab samples. All eight of the NDV isolates were identified as class I genotype 3 strains,but they diverged notablely from class II viruses. Further analysis revealed that alleight NDV isolates were lentogenic strains containing the112ERQER↓L117 motif at the F protein cleavage site. The strainswere highly identical and were more species specific (chicken and waterfowl) than sitespecific (Nanchang and Duchang regions). The close phylogenetic proximity of theseisolates indicates that viral transmission may happen between poultry and wild birds. Ourstudy demonstrates that lentogenic class I NDVs exist in clinically healthy wild waterfowland poultry within the Poyang Lake region. Active surveillance of these viruses todetermine their evolution and origin is one of the most realistic strategies forpreventing and controlling NDV outbreaks.

【 授权许可】

Unknown