Tubulopapillary Carcinoma with Spindle Cell Metaplasia of the Mammary Gland in a Cat

Journal of Veterinary Medical Science

Hiroyuki TANIYAMA²  Kazuko HIRAYAMA²  Kazuya MATSUDA²  Tsuyoshi KADOSAWA¹  Misato YAMASHITA¹  Shintaro KOBAYASHI² 

[1] Department of Small Animal Clinical Sciences, School of Veterinary Medicine, Rakuno Gakuen University;Department of Veterinary Pathology, School of Veterinary Medicine, Rakuno Gakuen University

关键词: feline;    mammary tumor;    spindle cell;   

DOI  :  10.1292/jvms.70.479

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(8)Cited-By(1)Sarcomatous proliferation of spindle cells was present in the mammary gland and many metastatic sites in a 10-year-old female domestic cat with tubulopapillary carcinoma in the mammary gland. Transition from neoplastic tubular structures to spindle cells in the primary site and fascicular proliferation of the spindle cells with or without coexistance of tubulopapillary carcinoma in the primary and metastatic sites were observed. Most of spindle cells were positive for cytokeratin CAM5.2 as well as the normal luminal epithelium but not the myoepithelium. From these results, this case was diagnosed as tubulopapillary carcinoma with spindle cell metaplasia and it was clarified that neoplastic luminal epithelial cells can transform to sarcomatous appearence.

【 授权许可】

Unknown