Intestinal T-Cell Lymphoma with Severe Hypereosinophilic Syndrome in a Cat

Journal of Veterinary Medical Science

Koichi OHNO²  Hajime TSUJIMOTO²  Masashi TAKAHASHI²  Kazuyuki UCHIDA¹  Masaya TSUBOI¹  Hiroyuki NAKAYAMA¹  Yasuhito FUJINO²  Yoshinori TAKEUCHI² 

[1] Department of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1–1–1 Yayoi, Bunkyo-ku, Tokyo 113–8657, Japan;Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1–1–1 Yayoi, Bunkyo-ku, Tokyo 113–8657, Japan

关键词: feline;    hypereosinophilia;    paraneoplastic syndrome;   

DOI  :  10.1292/jvms.12-0064

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(28)Cited-By(1)A Japanese domestic long-hair cat of about 8 years of age was presented with vomiting and hematochezia and was found to have significant hypereosinophilia. Bone marrow aspiration revealed moderate increases of eosinophilic lineages. Histopathological examination revealed mild eosinophilic and epitheliotropic T-lymphocytic infiltrations in the duodenum. Although the cat remained asymptomatic with only prednisolone administration, the cat presented with hematemesis, weight loss, and severe anorexia 512 days after the initial presentation. Subsequently, gastrointestinal perforation developed, and the cat died on Day 536. Histopathological examination of autopsy specimens revealed mixed cellular infiltration including eosinophils and neoplastic lymphocytes in the intestinal lymph nodes, intestine, liver, spleen, and pancreas. Immunohistochemical examination supports a diagnosis of intestinal T-cell lymphoma with severe hypereosinophilic syndrome.

【 授权许可】

Unknown