First isolation of enterovirus 71 (EV-71) from Northern Brazil

Brazilian Journal of Infectious Diseases

Gomes, Maria de Lourdes Contente¹  Maciel, Ana Maria T. R.¹  Lamarão, Leticia Martins¹ 

[1] Evandro Chagas Institute, Belém, Brazil

关键词: Enterovirus-71;    neurological disease;   

DOI  :  10.1590/S1413-86702003000400009

来源: Contexto

【 摘 要 】

Enterovirus 71 (EV-71) has been associated to cases of neurological disease in many countries including Brazil. This virus has now been reported from three of the five Brazilian regions. Our study relates the findings concerning to the first isolate of this virus in Northern region of Brazil. A 15-month old female patient, from the rural zone of the municipality of Santana do Araguaia in southern Pará state was admitted at the hospital with acute, flaccid, asymmetric and ascending motor deficiency, located in the right lower limb. Stools samples from this child were inoculated in RD cells and was isolated an EV-71. We plan to sequence our strain and compare it to other isolates in Brazil. Differences at the molecular level can explain why EV-71 strains circulating in other continents, such as Asia, appear to be more virulent.

【 授权许可】

CC BY-NC-ND