Technological development of a sedative medicine of natural origin from Justicia pectoralis Jacq

Revista Cubana de Plantas Medicinales

Gil Apan, José M¹  Rodríguez Chanfrau, Jorge¹  de la Paz Martín-Viaña, Nilia¹  López Hernández, Orestes D¹  González Sanabia, María Lidia¹  Fuste Moreno, Viviana M¹  Nogueira Mendoza, Antonio¹ 

[1] Centro de Investigación y Desarrollo de Medicamentos (CIDEM), La Habana, Cuba

关键词: estabilidad;    Justicia pectoralis Jacq;   

DOI  :  

学科分类：药理学

来源: Editorial Ciencias Medicas

【 摘 要 】

Introduction: the use of natural raw materials as active ingredient is increasingly spreading in the drug industry for the manufacture of pharmaceuticals. Justicia pectoralis Jacq.(Acantaceae) is a herbaceous plant traditionally used as sedative by the Cuban population which knows it as lime tea. Objective: to develop syrup containing the dry extract from J. pectoralis 0.6 % m/v as active principle. Methods: the formulation, microbiological and chemical/physical stability studies were performed on the product stored at room temperature in 125 mL amber-coloured glass containers. Results: the syrup had adequate organoleptic characteristics and was stable from the microbiological, physical and chemical viewpoints for 36 months under the studied conditions. Conclusions: this pharmaceutical was properly formulated from the galenic viewpoint and met all the set quality requirements for this type of pharmaceutical form.

【 授权许可】

CC BY-NC