Systemic Candidiasis and Mesenteric Mast Cell Tumor with Multiple Metastases in a Dog

Journal of Veterinary Medical Science

Hiroyuki TANIYAMA²  Kazuko HIRAYAMA²  Kazuya MATSUDA²  Tsuyoshi KADOSAWA¹  Kanako SAKAGUCHI²  Shintaro KOBAYASHI²  Makiko TOMINAGA¹ 

[1] Department of Small Animal Clinical Sciences, School of Veterinary Medicine, Rakuno Gakuen University;Department of Veterinary Pathology, School of Veterinary Medicine, Rakuno Gakuen University

关键词: candidiasis;    canine;    mast cell tumor;   

DOI  :  10.1292/jvms.71.229

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(18)Cited-By(2)A 5-year-old female miniature dachshund presenting with persistent vomiting and diarrhea had two concurrent rare pathological conditions: systemic candidiasis and mesenteric mast cell tumor with multiorgan metastases. Neoplastic mast cells formed mass in the mesentery of the cecal-colonic region and were also found in the liver, spleen, kidneys, lungs, adrenal grands, ovaries, bone marrow and other tissues. The cells had intracytoplasmic granules with metachromasia and were immunohistochemically positive for c-kit and histamine. Granulomatous lesions with fungal organisms were present in the heart, lungs, kidneys, pancreas, subserosal and surrounding adipose tissue of the duodenum, thyroid glands and mesenteric mass, and phagocytosed organisms were detected in the liver and bone marrow. Bacteriologically and immunohistochemically, the fungi were consistent with Candida albicans.

【 授权许可】

Unknown